Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus
نویسندگان
چکیده
منابع مشابه
Clinical manifestations of Lichen Planus: A report of 120 cases
Background: Lichen planus (LP) is an idiopathic papulosquamous disorder, which can show cutaneous or mucosal signs. It is caused by a cell mediated immune response to an antigen. A wide range of clinical manifestations has been reported. Objective: To determine the sex and age frequency and clinical presentations of this disease in patients referred to Razi hospital in Tehran. Patients and Meth...
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Erosive lichen planus is an uncommon variant of lichen planus. Chronic erosions of the soles, accompanied by intense and disabling pain, are some of its most characteristic manifestations. We present the case of a woman who developed oral and plantar erosive lichen planus associated with lichen planus pigmentosus and ungueal lichen planus that were diagnosed after several years. The patient fai...
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Lichen planus (LP) skin lesions are often accompanied by itch, but this symptom has not been thoroughly examined in LP. To better characterize itch in LP, 78 patients with LP were investigated. Itch was present in 94.9% of patients and was usually described as the most vexing symptom of LP. The mean?±?SD severity of itch according to visual analogue scale score was 6.9?±?2.8 points. Most patien...
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T ERMATOSES of diverse etiology have been -I-~ reported to give rise to skin and mucous membrane lesions whose morphology, symptomatology, course, and microscopic picture cannot be distinguished from lichen planus. Drugs,1-6 vaccines,7 contact with chemicals,8-'3 and exposure to ultraviolet light and Grenz rays14 are prominent among the causative agents which have been observed to produce liche...
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We describe a fifty-six-year old, Afro-descendent female patient showing dystrophy of her twenty nails and hyperchromic, asymptomatic macule on her face. Histopathological examination of the macule showed vacuolization of the basal layer, melanophages in the superficial dermis and lymphoplasmocytic inflammatory infiltrate. Nail biopsy revealed orthokeratotic hyperkeratosis and lichenoid inflamm...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2019
ISSN: 1664-3224
DOI: 10.3389/fimmu.2019.01808